Journal: Journal of Traditional and Complementary Medicine
Article Title: Tiaojing Cuyun Recipe inhibits ferroptosis through SLC7A11/GSH/GPX4 axis to improve endometrial receptivity of mice with embryo implantation dysfunction
doi: 10.1016/j.jtcme.2025.03.005
Figure Lengend Snippet: TJCYR regulates cystine metabolism and inhibits ferroptosis in EID mice through SLC7A11-GSH-GPX4 axis. A–F: GSH, Reduced Glutathione, GSH-Px, T-GSH, GSSG and GSH/GSSG level in serum of mice in each group. Data are expressed as mean ± standard deviation (n = 5). ∗ P < 0.05 versus control; # P < 0.05 versus EID. G–J: Western blot analysis of GPX4、SLC7A11 and COX2 in mice of each group. Data are expressed as mean ± standard deviation (n = 4). ∗ P < 0.05 versus control; # P < 0.05 versus EID. K–M: Expression of GPX4, SLC7A11 and COX2 immunofluorescence intensity in endometrium of mice in each group.
Article Snippet: Reduced glutathione (E-BC-K030-M), GSH-Px activity (E-BC-K096-M), T-GSH/GSSG colorimetric (E-BC-K097-M), QuicKey Pro Mouse Pg (Progesterone) (E-OSEL-M0006), Quick EY Pro Mouse E 2 (estradiol) (E-OSEL-M0008), and MDA colorimetric (TBA method) (E-BC-K025-M) assay kits were purchased from Elabscience (USA).
Techniques: Standard Deviation, Control, Western Blot, Expressing, Immunofluorescence